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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T72684 | TLR7/8 agonist 7 | ||
TLR7/8 agonist 7, a compound that functions as a TLR7/8 agonist, plays a pivotal role in activating various immune cells and is instrumental in the synthesis of immune-stimulating antibody conjugate (ISAC) molecules. Thi... | |||
T5561 | TLR7/8 agonist 1 dihydrochloride | TLR7/8 agonist-5d | TLR |
TLR7/8 agonist 1 dihydrochloride (TLR7/8 agonist-5d) is a TLR7/8 agonist which shows prominent immunostimulatory activities. | |||
T13167 | TLR7/8 agonist 3 | TLR | |
TLR7/8 agonist 3 is a potent agonist of TLR7 and TLR8. | |||
T39969 | TLR7/8 agonist 4 TFA | ||
TLR7/8 agonist 4 TFA (compound 41) is a highly potent TLR7/8 agonist that exhibits significant anti-cancer activity. | |||
T39968 | TLR7/8 agonist 4 hydroxy-PEG10-acid | TLR7/8 agonist 4 hydroxy-PEG10-acid | |
TLR7/8 agonist 4 hydroxy-PEG10-acid (compound 9) is a drug-linker conjugate employed in antibody-drug conjugates (ADC). This compound exhibits remarkable antitumor activity by utilizing TLR7/8 agonist 4, which acts as a ... | |||
T39970 | TLR7/8 agonist 4 hydroxy-PEG10-acid hydrochloride | TLR7/8 agonist 4 hydroxy-PEG10-acid hydrochloride | |
TLR7/8 agonist 4 hydroxy-PEG10-acid hydrochloride (compound 9) is a drug-linker conjugate used in antibody-drug conjugates (ADCs) with high efficacy against tumors. It consists of TLR7/8 agonist 4, a potent TLR7/8 agonis... | |||
T17032 | Telratolimod | MEDI9197,3M-052 | TLR |
Telratolimod (MEDI9197) is a toll-like receptors 7/8 agonist. It has an antitumor activity. | |||
T6964 | Resiquimod | R848,S28463 | HCV Protease , TLR |
Resiquimod (R848) is an imidazoquinoline amine and Toll-like receptor (TLR) agonist with potential immune response modifying activity. Resiquimod exerts its effect through the TLR signaling pathway by binding to and acti... | |||
T79068 | TLR7/8 agonist 8 | ||
TLR7/8 agonist 8 (compound 24m) is a potent dual agonist for toll-like receptors 7 and 8 (TLR7/8), exhibiting half-maximal effective concentrations (EC50s) of 27 nM for human TLR7 (hTLR7) and 12 nM for human TLR8 (hTLR8)... | |||
T62177 | TLR7/8 agonist 6 | ||
TLR7/8 agonist 6 (Compound 4), an imidazoquinoline derivative, is a potent TLR7/8 agonist with IC50 values of 0.18 and 5.34 μM for TLR7 and TLR8, respectively. TLR7/8 Antagonist | |||
T62178 | TLR7/8 antagonist 1 | ||
TLR7/8 Antagonist 1 (Compound 16c), an imidazoquinoline derivative, is a potent TLR7/8 agonist with IC50 values of 3.91 and 2.19 μM for TLR7 and TLR8, respectively. rel-O-2050 (TLR-2050) is a key target for drug developm... |